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Cumulative Risk of Adverse Obstetric Outcomes in Pregnant Women With Fibroids

FibroidsNo FibroidsP ValueUnadjusted OR (95% CI)
Cesarean delivery48.8% (2098/4322)13.3% (22,989/173,052)<.0013.7 (3.5–3.9)
Malpresentation13.0% (466/3585)4.5% (5864/130,932)<.0012.9 (2.6–3.2)
Labor dystocia7.5% (260/3471)3.1% (4703/148,778)<.0012.4 (2.1–2.7)
Postpartum hemorrhage2.5% (87/3535)1.4% (2130/153,631)<.0011.8 (1.4–2.2)
Peripartum hysterectomy3.3% (18/554)0.2% (27/18,000)<.00113.4 (9.3–19.3)
Retained placenta1.4% (15/1069)0.6% (839/134,685).0012.3 (1.3–3.7)
Chorio or endometriosis8.7% (78/893)8.2% (2149/26,090).631.06 (0.8–1.3)
IUGR11.2% (112/961)8.6% (3575/41,630)<.0011.4 (1.1–1.7)
Preterm labor16.1% (116/721)8.7% (1577/18,187)<.0011.9 (1.5–2.3)
Preterm delivery16.0% (183/1145)10.8% (3433/31,770)<.0011.5 (1.3–1.7)
Placenta previa1.4% (50/3608)0.6% (924/154,334)<.0012.3 (1.7–3.1)
First-trimester bleeding4.7% (120/2550)7.6% (1193/15,732)<.0010.6 (0.5–0.7)
Abruption3.0% (115/4159)0.9% (517/60,474)<.0013.2 (2.6–4.0)
PPROM9.9% (123/1247)13.0% (7319/56,418).0030.8 (0.6–0.9)
PPROM or PROM6.2% (217/3512)12.2% (7425/60.661)<.0010.5 (0.4–0.6)