What are appropriate interventions for a person with COPD who is showing signs of respiratory failure?

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Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.

When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.

Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.

What causes respiratory failure?

Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include:

  • Diseases that affect the lungs, such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, pulmonary embolism, and COVID-19
  • Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
  • Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
  • Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
  • Drug or alcohol overdose
  • Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes

What are the symptoms of respiratory failure?

The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.

A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.

Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.

How is respiratory failure diagnosed?

Your health care provider will diagnose respiratory failure based on:

  • Your medical history
  • A physical exam, which often includes
    • Listening to your lungs to check for abnormal sounds
    • Listening to your heart to check for arrhythmia
    • Looking for a bluish color on your skin, lips, and fingernails
  • Diagnostic tests, such as
    • Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
    • Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.

Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.

What are the treatments for respiratory failure?

Treatment for respiratory failure depends on:

  • Whether it is acute (short-term) or chronic (ongoing)
  • How severe it is
  • What is causing it

Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.

One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include:

  • Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
  • Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
  • Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
  • Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
  • Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
  • Medicines for discomfort
  • Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.

If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.

If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.

Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.

NIH: National Heart, Lung, and Blood Institute

The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health.

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People with chronic obstructive pulmonary disease (COPD) may occasionally have symptom exacerbations, or flare-ups. Treatments options for exacerbations include bronchodilators, corticosteroids, antibiotics, oxygen therapy, and ventilation.

COPD is the name given to a group of long-term lung diseases. The condition tends to get worse over time and symptoms can include:

  • wheezing
  • shortness of breath
  • coughing
  • excess mucus production
  • chest tightness
  • fatigue

People with COPD may occasionally notice that their symptoms suddenly get worse, or that new symptoms develop. Doctors refer to these periods as exacerbations, or flare-ups.

In some people, certain things, such as an infection, a change in the weather, or exposure to irritants or allergens, can trigger an exacerbation.

In this article, learn about some of the options for treating a COPD exacerbation. We also discuss the importance of treating exacerbations, when hospitalization may be necessary, and some tips for preventing exacerbations.

Generally, the sooner a person begins treatment for a COPD exacerbation, the better. Several treatment options are available, including:

Bronchodilators

What are appropriate interventions for a person with COPD who is showing signs of respiratory failure?
Share on PinterestA bronchodilator can open the lungs to ease the symptoms of a COPD exacerbation.

Bronchodilators are medications that relax the muscles of the airways, which helps them open up. One of the most common bronchodilators that doctors prescribe for people with COPD is albuterol.

A COPD exacerbation may result in increased chest tightness, wheezing, or shortness of breath. Taking medication to open the lungs, such as a bronchodilator, can help ease these symptoms.

Bronchodilators typically come in the form of an inhaler device or a liquid. To take the liquid form, a person must use a machine called a nebulizer to turn the liquid into an aerosol or mist, which a person can then inhale into the lungs.

Side effects of using a bronchodilator may include a faster heart rate, a headache, and shakiness.

Corticosteroids

Increased inflammation of the lungs and airways can trigger a COPD exacerbation. Corticosteroids can help reduce this inflammation and relieve symptoms.

Corticosteroids come in many forms, including tablets, inhaler devices, and injections. Corticosteroids that doctors commonly prescribe for the treatment of COPD exacerbations include prednisone and budesonide.

Corticosteroids can cause systemic side effects, especially when a person takes them intravenously or orally. Systemic side effects can affect the whole body.

Possible side effects include increased blood sugar, nervousness, and headache. Nebulized corticosteroids may cause hoarseness, dry mouth, or oral yeast infections.

The best way to administer corticosteroids to treat a COPD exacerbation depends on the type and severity of symptoms. However, the results of a 2014 study suggest that nebulized corticosteroids may be as effective as intravenous corticosteroids but with fewer systemic side effects.

Antibiotics

People with COPD are more likely to develop a lung infection than those without the lung disease. These infections can lead to an exacerbation, and people with COPD may be more likely to experience complications from lung infections.

If a doctor suspects that a person with COPD has a bacterial infection, they may prescribe them a course of antibiotics.

The results of a 2013 study that involved 53,900 participants suggest that adding antibiotics to a treatment plan that also included corticosteroids may briefly improve symptoms for people in the hospital with a COPD exacerbation.

Oxygen therapy

A person’s oxygen levels may decrease during a COPD exacerbation. Oxygen therapy can help improve oxygen levels in the blood and ease the related symptoms, such as shortness of breath.

During oxygen therapy, a person will inhale oxygen from a machine through a mask or via nasal tubes. People can use an oxygen therapy machine at home.

Noninvasive ventilation

What are appropriate interventions for a person with COPD who is showing signs of respiratory failure?
Share on PinterestPeople with severe COPD exacerbation may need treatment with noninvasive ventilation.
Image credit: James Heilman, 2014

Noninvasive ventilation (NIV) is a type of respiratory support that can improve oxygen levels, inflate the lungs, and make breathing easier. NIV involves a machine that delivers pressure and oxygen to the lungs through a mask.

Doctors will typically provide NIV to people in the hospital with a severe COPD exacerbation.

A 2017 study reviewed 17 clinical trials that involved 1,264 people who were in the hospital with COPD. The researchers found that participants who underwent NIV had a 46 percent lower risk of death than those who did not undergo NIV.

NIV treatment also reduced the length of hospital stays and lowered the risk of experiencing COPD-related complications.

Intubation and ventilation

During intubation, a specialist will insert a breathing tube into a person’s windpipe to allow for mechanical ventilation, or assisted breathing. The specialist will then connect the breathing tube to a ventilator, which is also known as a breathing machine or a respirator.

Doctors may use a ventilator if a person is unable to breathe on their own, or their breathing is ineffective at removing carbon dioxide or oxygenating the lungs.

The machine can deliver a set number of breaths per minute, a volume of air, and pressure to the lungs. It also delivers oxygen.

It is critical for a person to begin treatment for a flare-up of COPD symptoms as soon as possible. Exacerbations can trigger a decrease in oxygen levels in the blood or issues removing carbon dioxide from the body, which can result in respiratory failure.

Recognizing the signs of a COPD exacerbation quickly and seeking appropriate treatment may prevent a flare-up from becoming life-threatening.

A person may treat a COPD exacerbation at home using oxygen and medications. However, there may be other cases in which hospitalization is needed.

At the hospital, medical professionals can continuously monitor a person, as well as administer specialized treatment.

Signs that a person with COPD may need to go to the hospital include:

  • getting no relief from the use of inhalers
  • experiencing confusion or a decreased level of consciousness
  • noticing swelling in the legs or feet
  • feeling chest pain
  • having fingers, toes, or lips that are bluish or gray

COPD exacerbations are events during which a person’s symptoms suddenly become worse or new symptoms develop. Certain strategies, such as avoiding triggers, can help reduce the chance of experiencing a COPD exacerbation. However, it is not always possible to prevent them.

Treatment depends on the type and severity of the exacerbation and can include bronchodilators, corticosteroids, antibiotics, oxygen therapy, and ventilation. Sometimes, a person may need more than one form of treatment.

Prompt recognition and treatment of a COPD exacerbation can reduce the need for hospitalization and may lower the risk of complications. A doctor can provide a treatment and action plan for dealing with exacerbations.